MRI Patterns of Brain Toxicity

Toxicity of atorvastatin on isolated brain mitochondria

Background: Although the bio kinetics, metabolism and chemical toxicity of Atorvastatin are well known, until recently little attention was paid to the potential neurotoxic effect of Atorvastatin (Atv). Regarding the concrete evidences indicating Atv may reduce Coenzyme Q10 (CoQ10) levels through blockage of  metalonate cycle, the present work aims to determine if Atorvastatin may provide toxic...

Brain MRI Findings in Tramadol Poisoning

Protective effect of ginger on diazinon-induced brain toxicity

Background and objectives: Diazinon (DZN), an organophosphate insecticide, is widely used in agriculture. One of its deleterious effects is on neural systems. Diazinon with acetylcholinesterase activity and lipid peroxidation induces brain toxicity . Ginger, as a medicinal plant, has antioxidant and anti-imflammatory properties. The aim of present study was to evaluate...

Brain MRI Findings in Children with Acute Lymphoblastic Leukemia

Background: Patients with leukemia are facing more complications in order to achieve longer survival. We aimed to evaluate the frequency of central nervous system abnormalities (CNS) on MRI of children with acute lymphoblastic leukemia (ALL). Methods: Sixty-six children with diagnosis of ALL aged 2-18 years were recruited. Non-contrast sequences of brain MRI in addition to diffusion weighted i...

Segmentation of Brain MRI

Effective, precise and consistent brain cortical tissue segmentation from magnetic resonance (MR) images is one of the most prominent issues in many applications of medical image processing. These applications include surgical planning (Kikinis et al., 1996), surgery navigation (Grimson et al., 1997), multimodality image registration (Saeed, 1998), abnormality detection (Rusinek et al., 1991), ...